Secondary osteoporosis: differential diagnosis and workup There are numerous causes of secondary osteoporosis including endocrine disorders, nutritional deficiencies, and other miscellaneous conditions and medications. It is essential to identify and address these factors to appropriately manage patients with osteoporosis.

2020-05-13

Objectives: Outline the causes of secondary osteoporosis. Workup. There are numerous causes of secondary osteoporosis including endocrine disorders, nutritional deficiencies, and other miscellaneous conditions and medications. It is essential to identify and address these factors to appropriately manage patients with osteoporosis. The presence of secondary causes of bone loss may further increase the risk of fracture independently of BMD and may necessitate earlier pharmacologic intervention. Dual-energy X-ray absorptiometry is indicated in the initial workup of secondary causes of osteoporosis. Secondary causes of osteoporosis are less common than primary osteoporosis, but correctly treating an underlying cause may be sufficient to ameliorate the increased fracture risk.

Secondary osteoporosis workup

What causes osteoporosis in children? In children, the following medical conditions or medications can lead to osteoporosis. Secondary osteoporosis. These are with osteoporosis to specialist care for a full diagnostic workup to avoid missing the less common causes of secondary osteoporosis.

In cases of secondary osteoporosis, the loss of bone mass is caused by certain lifestyle behaviors, diseases, or medications. Some of the most common causes of secondary osteoporosis in men include exposure to glucocorticoid medications, hypogonadism (low levels of testosterone), alcohol abuse, smoking, gastrointestinal disease, hypercalciuria, and immobilization.

every 1–2 years in adulthood is useful to evaluate for possible osteoporosis. Secondary osteoporosis: differential diagnosis and workup There are numerous causes of secondary osteoporosis including endocrine disorders, nutritional deficiencies, and other miscellaneous conditions and medications. It is essential to identify and address these factors to appropriately manage patients with osteoporosis. This basic laboratory workup will identify patients with the relatively common secondary causes of low bone mineral density which account for 98% of all cases.

Secondary Fracture Prevention: An International Perspective: Seibel, Markus: the rationale for pursuing a workup to prevent fractures in this patient population. osteoporosis, fragility fracture prevention, orthogeriatrics, fracture registries,

There is an inverse relationship between Z-scores and the presence of causes of secondary osteoporosis. 2020-11-21 · It is useful when suspecting secondary osteoporosis. A score is less than negative 1.5 warrants a workup for secondary causes of osteoporosis. The low bone density of the hip has the highest predictive value of future fracture. Secondary osteoporosis is not an uncommon condition.

Before sharing sensitive information, make sure you're on a federal government site. The site is secure. The https:// ensur Drugs called bisphosphonates are the most common treatment for osteoporosis. Some other drugs may be tried if these are ineffective. All drug therapies should be combined with a healthy diet and regular exercise to lower risk of bone fractu Osteoporosis can cause bones to become brittle and weak, putting a person a risk of fracture. Think you may have arthritis? Learn about the four most common warning signs.
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These causes include vitamin D deficiency, malabsorption, hypogonadism, hypercalciuria, and myeloma. “Leave the other 2% to me,” the rheumatologist suggested. Secondary forms of osteoporosis are listed in Table 1. 8 If secondary osteoporosis is suspected, appropriate diagnostic work-up could identify a different management course. For example, if a In patients with newly diagnosed osteoporosis, suggested laboratory tests to identify secondary causes include serum 25-hydroxyvitamin D, calcium, creatinine, and thyroid-stimulating hormone.

Clin Obstet Gynecol. 2013; 56(4):686-93 (ISSN: 1532-5520) Diab DL; Watts NB. There are numerous causes of secondary osteoporosis including endocrine disorders, nutritional deficiencies, and other miscellaneous conditions and medications.
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One reasonable diagnostic approach is described here. If your doctor did things differently, that doesn’t mean that he or she was wrong or that this approach is wrong. Every case should be treated individually.

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Workup. There are numerous causes of secondary osteoporosis including endocrine disorders, nutritional deficiencies, and other miscellaneous conditions and medications. It is essential to identify and address these factors to appropriately manage patients with osteoporosis.

2018-03-04 Endocrinologists more frequently performed a workup for secondary causes of osteoporosis compared to other provider specialties.

Primary osteoporosis is bone loss that occurs during the normal human aging process. Secondary osteoporosis is defined as bone loss that results from specific, well-defined clinical disorders. Many times reversible, secondary causes of bone loss are not considered in a patient with low bone mineral density (BMD). Secondary osteoporosis may be

We also found a significant amount of vitamin D deficiency/insufficiency and primary hyperparathyroidism in the population evaluated.

A growing understanding of other factors that contribute to the susceptibility of fragility fractures, many of which are not reflected in BMD testing, has expanded the spectrum of patients considered at risk and in need of a workup. Secondary osteoporosis is loosely defined as low bone mineral density or increased risk of fragility fracture for a careful diagnostic workup. According to the 2018 update of the Portuguese recommendations for the prevention, diagnosis and management of OP[7], secondary OP (SOP) should be suspected in the presence of: a) conditions known to induce osteoporosis (Table 1); b) in the presence of fragility fractures occurring before the age of 70 for men or RESULTS: We found that among providers ordering DXAs, primary care providers did not pursue recommendations to pursue a secondary workup as often as their subspecialty counterparts. We also found a significant amount of vitamin D deficiency/insufficiency and primary hyperparathyroidism in the population evaluated. Bone densitometry using dual energy x ray absorptiometry should be performed in patients with vertebral fractures to establish whether low bone mineral density is present Secondary causes of osteoporosis are present in about 30% of women and 55% of men with vertebral crush fractures Secondary causes of osteoporosis may be associated with physical findings, such as nodular thyroid, hepatic enlargement, cushingoid features, skin rashes, jaundice, abnormal dentition, and findings of hypogonadism. Secondary osteoporosis - an endocrinological approach focusing on underlying mechanisms. Polymeris A, Michalakis K, Sarantopoulou V. Osteoporosis is a major and increasingly serious public health problem not only in postmenopausal women and people over 70 years old (primary osteoporosis) but also in men under 70 years and premenopausal women Osteoporosis is a skeletal disease characterized by decreased bone mass and microarchitectural changes in bone tissue that increase the susceptibility to fracture.